Antinuclear antibodies and lupus: causes and consequences
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چکیده
منابع مشابه
Hydralazine antinuclear antibodies and the lupus syndrome.
The incidence of patients with positive antinuclear antibody test results rose during three years of treatment with hydralazine. At the end of that period over half of the patients (both rapid and slow acetylators) had titres exceeding 1/20, but the rate of rise was faster in the slow acetylators than in the rapid. There was a significant relation between the cumulative dose of hydralazine and ...
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Autoantibodies to the three extractable nuclear antigens (ENA), Anti-SSA (Ro), Anti-Sm, Anti-RNP and antinuclear antibodies were determined in 150 patients with SLE. Seventy patients (46.7%) had Anti-SSA (Ro), 40 (26.7%) Anti-Sm and 25 (16.7%) Anti-RNP antibodies. Ninety four percent patients had a positive Fluorescent anti-nuclear antibody (FANA) test. The commonest FANA pattern is the speckle...
متن کاملAntinuclear Antibodies
knowledge of gene regulation, particularly in neoplastic cells, this deficit is striking. With our current understanding of chromosomal translocations, point mutations, and gene amplification in tumor cells, it is surprising to read that there is ". . . no difference between cancer and normal DNA . . ." (p. 130). The author spends a fair amount of time discussing possible mechanisms for the car...
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Introduction: Infertility has various and innumerable causes, which pointing them out one by one is difficult and out of the scope of this paper. Infertility causes are different between males and females, and each case requires a separate and thorough research. The present study aimed to identify the male infertility causes. Methods: This study was conducted using a qualitative method, which ...
متن کاملIgG, IgM, and IgA Antinuclear Antibodies in Discoid and Systemic Lupus Erythematosus Patients
IgG antinuclear antibodies (ANAs) are elevated in patients with systemic lupus erythematosus (SLE) compared with patients with discoid lupus erythematosus (DLE). To provide an expanded immunologic view of circulating ANAs in lupus patients, we compared the expressions of IgG, IgM, and IgA ANAs in DLE and SLE patients. In this cross-sectional study, sera from age-, gender-, and ethnic-matched SL...
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ژورنال
عنوان ژورنال: Rheumatology
سال: 1999
ISSN: 1462-0332,1462-0324
DOI: 10.1093/rheumatology/38.8.691